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New study: Hearing loss can be reversed through Viagra use

2025-11-22 20:59:00, Shëndeti CNA

New study: Hearing loss can be reversed through Viagra use

A new study found that hearing loss caused by mutations in a certain gene at birth can be reversed by a common supplement along with the erectile dysfunction drug Viagra (sildenafil).

Researchers identified mutations in a gene known as CPD, which produces the enzyme carboxypeptidase D, among three unrelated families from Turkey in which many people were born deaf.

These families all had a form of inherited sensorineural hearing loss, a condition caused by damage to the tiny hair cells in the inner ear that convert sound vibrations into electrical signals sent to the brain, according to the National Institutes of Health.

To better understand the link, the scientists compared the genetic data of affected and unaffected relatives within these families. They then extended their analysis to other groups.

"We then found that CPD mutations are present in people with hearing loss in a large genome sequencing cohort from England," said study author Dr. Mustafa Tekin, professor of human genetics and chair of the Department of Human Genetics at the University of Miami Miller School of Medicine.

After "turning off" the CPD gene in human cells in laboratory tests, researchers observed reduced levels of three substances: arginine (an amino acid), cyclic guanosine monophosphate (cGMP, an important signaling molecule), and nitric oxide, which provides vital signals to the nervous system. /CNA

 





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